Summary: Reprogramming somatic cells into induced pluripotent stem cells (iPSCs) involves the reactivation of endogenous pluripotency genes and global DNA demethylation, but temporal resolution of these events using existing markers is limited.Here, we generate murine transgenic lines harboring reporters for the 5-methylcytosine dioxygenase Tet1 an

This article explores the complex intersections between the roles of physician and writer, focusing on the interpretive challenges inherent in this twofold identity.The works of Dannie Abse (1923-2014), a Welsh-Jewish writer and chest physician, serve as an ideal case study to explore these epistemological tensions and examine some of the intricaci

Functional neuroimaging methods like fMRI and PET are vital in neuroscience research, but require that subjects remain still throughout the scan.In animal research, anesthetic agents are typically applied to facilitate the acquisition of high-quality data with minimal motion artifact.However, anesthesia can have profound effects on brain metabolism

Executive Summary Capital structure decisions are vital for firms.Existing theories on capital Rattles structure partially explain the difference in capital structure decisions of identical firms.Researchers have integrated psychology with finance in recent years to explain the difference in capital structure decisions better.To help practitioners